iGERD News
| 2012-02-20 | iGERD-Metabolic: Diabetes positively associates with Barrett‘s esophagus. Source: Keyashian K, Hua V, Kline M, Chandrasoma PT, Kim JJ. Dis Esoph 2012, ahead of print. Barrett‘s esophagus is positively linked to diabetes, male gender, age > 55 years, NSAID/ASA use. Implications for screening and... | read article |
| 2012-02-20 | Argumente für HALO® Ablation von Barrett Ösophagus. Source: iGERD news room Argumente für Radiofrequenz Ablation (HALO® Ablation) von Barrett Ösophagus ohne Dysplasie. ... | read article |
| 2012-02-16 | Körper-Seele-GERD-Gestimmtheit: Wohlfühlen ist das Ziel. Source: iGERD news room Sie suchen Rat, weil Sie sich nicht wohlfühlen, weil Ihre Gestimmtheit nicht gut ist. ... | read article |
| 2012-02-15 | GERD Diagnosis: Junction Pressure Topography. Go for high resolution manometry. Source: Kahrilas PJ, Peters HJ. Neurogastroetnerol Motil 2012; 24(Suppl 1): 11-19. High resolution manometry assesses the pressure topography of the esophago-gastric junction, which is impaired in GERD patients.... | read article |
| 2012-02-15 | STRESS and GERD. Implications for the holistic GERD management. Source: Konturek PC, Brzozowski, Konturek SJ. Journal of Physiology and Pharmacology 2011; 62, 6, 591-599. STRESS promotes reflux and the perception of reflux. Therefore elimination of stress should be included into modern GERD manage... | read article |
| 2012-02-10 | Eosinophilic esophagitis increased in cold and arid climate zones. Source: Am J Gastroenterol, 2012; ahead of print. Hurrell JM, Genta RM, Dellon ES. Cold and arid climate favors "allergic" eosinophilic esophagitis.... | read article |
| 2012-02-10 | Neue elegante Anti-Reflux Operation: Magnetischer Speiseröhren Ring gegen Reflux; eine wirksame Alternative zur Fundoplikatio. Source: Bonavina L, DeMeester T, Fockens P, et al. Ann Surg 2010; 252,5: 857-862. Magnetischer Ring um den Ausgang der Speiseröhre verhindert Reflux. OP-Dauer 20 min. ... | read article |
| 2012-02-09 | Endoscopy of Barrett's esophagus: white light vs. narrow band imaging. Source: Sharma P, Hawes RH, Bansal A, et al. Gut 2012; ahead of print. Both endoscopic tests are equally effective to assess Barrett‘s esophagus without dysplasia. White light endoscopy or a combinat... | read article |
| 2012-02-08 | Radiofrequency ablation with or without prior endoscopic mucosal resection: does outcome differ? Source: Okoro NI, Tomizawa Y, Dunagan KT, et al. Clin Gastroenterol Hepatol, 2012; 10(2): 150-54. Prior endoscopic mucosal resection (EMR) does not impair safety and outcome of radiofrequency ablation (RFA) of Barrett‘s esopha... | read article |
| 2012-02-07 | Highly effective: PPI against GERD induced sleep disturbance. Source: Regenbogen E, Helkin A, Georgopoulos R, et al. Otolaryngol Head Neck Surg 2012, ahead of print. PPI therapy is highly effective to eliminate GERD induced sleep disturbance (night time reflux episodes).... | read article |
| 2012-02-07 | NEW: electrical stimulation restores the pressure of the anti-reflux mechanism. Source: Rodriguez L, Rodriguez P, Neto MG, et al. Neurogastroenterology & Motility 2012, ahead of print. Electrical stimulation restores the function of the lower esophageal sphincter (LES) in patients with small hernias (early GERD)... | read article |
| 2012-02-07 | Proton pump inhibitor (PPI): number of reflux episodes remains the same. Source: Clayton SB, Rife CC, Singh ER, Kalbfleisch JH, Castell DO. Dis Esophagus 2012, ahead of print. PPI therapy does not alter the frequency of reflux episodes. PPI alters the pH of the reflux. This explains why other therapies ... | read article |
| 2012-02-06 | Barrett‘s esophagus: loss of autophagy in dysplasia and cancer. Arguments for radiofrequency ablation of non-dysplastic Barrett‘s esophagus. Source: Roesly HB, Khan MR, Chen HDR, et al. Am J Physiol 2012; ahead of print. Autophagy mediated by Beclin-1 cleans the esophageal mucosa from premalignant epithelium. Beclin-1 expression and autophagy are ... | read article |
| 2012-01-30 | Ghrelin improves the nutritional status during chemotherapy for esophageal cancer. Source: Cancer 2012, ahead of print. Cisplatin based chemotherapy is applied for the treatment of advanced esophageal cancer. Administration of the gut hormone ghrel... | read article |
| 2012-01-26 | From high grade dysplasia to cancer: 25% in 6 months. Endoscopic therapy (ablation) decreases cancer risk. Source: Verbeek RE, van Oijen MGH, ten Kate FJW, et al. Am J Gastro, 2012 ahead of print. Within 6 months 25% of persons with high grade dysplasia developed esophageal adenocarcinoma. Ablation therapy decreased cancer ... | read article |
| 2012-01-26 | Increased toenail zinc ad cobalt concentration associates with Barrett‘s esophagus. Source: O‘Rorke MA, Cantwell MM, Abnet CC, et al. Int J Cancer 2012; ahead of print. Increased concentration of zinc ad cobalt associates with increased risk for Barrett‘s esophagus. ... | read article |
| 2012-01-26 | Cigarette smoking positively correlates with Barrett‘s esophagus. Source: Cook MB, Shaheen NJ, Anderson LA, et al. Gastroenterology 2012; ahead of print. Cigarette smoking is associated with an increased risk for Barrett‘s esophagus. Screening endoscopy should be offered to smokers... | read article |
| 2012-01-26 | GERD treatment centers: holistic, effective and durable. Source: iGERD news room The aim of successful management is to restore life quality, productivity and good vibrations (body and soul balancing). Special... | read article |
| 2011-11-17 | Development of Columnar Lined Esophagus in Man: Role of BMP-4 & CDX2. Source: J Gastrointest Surg 2011; ahead print (11. Nov. 2011) Model of columnar lined esophagus after esophagectomy describes the formation of cardiac mucosa via BMP-4 and CDX2. Paper has ma... | read article |
| 2011-11-10 | Screening for esophageal adenocarcinoma and colorectal cancer at 50 years of age. Source: Am J Gastroenterol 2011, 106(2): 254-60. Meta-analyses indicate that upper GI screening endoscopy is recommended for persons 50 years of age, irrespective of the presenc... | read article |
| 2011-11-09 | Costs for Management of Esophageal Cancer. Source: Br J Surg 2011; 98: 1589-98. Healthcare resource use and medical costs for the management of esophageal cancer. Gordon LG, Eckermann S, Hirst NG, et al. | read article |
| 2011-11-09 | Effective Screening for Cancer Prevention: The Proof is On Air. Source: iGERD NEWS ROOM Screening aims to prevent cancer by detection and elimination of pre-cancerous lesions. Literature indicates that screening for ... | read article |
| 2011-11-08 | Endoscopic vs. Laparoscopic Fundoplication Source: Surg Endosc 2011; ahead print; online version Nov 1, 2011 Laparoscopic fundoplication (Nissen) is superior to endoscopic fundoplication in terms of symptom relief. Both methods achieve c... | read article |
| 2011-11-07 | Screening Endoscopy for Barrett‘s Esophagus: women and men at age 50. Source: Gastrointest Endosc 2010, 71(1): 21-27. Women & men, 50 years of age, without and with symptoms of reflux (heartburn etc.) should be offered upper GI endoscopy + biopsy... | read article |
| 2011-11-07 | Reflux-Krankheit & Gier Source: iGERD NEWS ROOM Reflux ist ein Zeichen für Gier, diese schädigt, zersetzt Körper & Geist. Leben Sie gegen die Gier mit: Mässigung, Zurückhaltung... | read article |
| 2011-11-03 | Management von Barrett Ösophagus: Konzert zwischen Peripherie-Spital & spezialisiertem Zentrum Source: iGERD NEWS ROOM Barrett Ösophagus Management ist komplex & sollte zwischen Peripherie-Spitälern & Universitätskliniken aufgeteilt sein.... | read article |
| 2011-11-03 | Meta-analysis: Nissen Fundoplication with vs. without division of the short gastric vessels. Source: Surg Endosc 2011, ahead print. Nissen ± division of the short gastric vessels results in comparable outcome. Difference: division increases OP time and hospita... | read article |
| 2011-11-03 | Histopathology of normal esophagogastric junction in 714 GERD patients: 100% columnar lined esophagus (CLE); 22.5% Barrett‘s Esophagus!!! Source: Am J Surg Pathol 2011; ahead print. 100% of GERD patients with normal endoscopy have columnar lined esophagus, 22.5% have premalignant Barrett's esophagus. If norma... | read article |
| 2011-11-02 | Screening of Barrett's esophagus: Let us extend the indication Source: NEJM 2011; 365: 1375-83. Indication for screening endoscopy for Barrett's esophagus is to be redefined, in order to become effective for cancer preventio... | read article |
| 2011-11-02 | Barrett's esophagus in Szeged, Hungary Source: Dis Esoph 2011, ahead print With accurate endoscopy, biopsy sampling and histopathology you will find Barrett's esophagus in more than 25% of the cases.... | read article |
| 2011-10-31 | Barrett Ösophagus: Fakten, Zahlen & Konsequenz Source: iGERD NEWS ROOM Rezente Daten zu Barrett Ösophagus: Pro & Kontra ihn zu entfernen. ... | read article |
| 2011-10-31 | Krebsprävention: Vorsorge-Endoskopie der Speiseröhre bei Barrett Ösophagus Source: iGERD NEWS ROOM Speiseröhre-Krebsvorstufen-Früherkennung durch Vorsorge Gastroskopie ab dem 45. Lebensjahr (zusammen mit der Dickdarmspiegelung)... | read article |
| 2011-10-28 | Sugar metabolism, GERD and Barrett's esophagus: role of insulin. Source: Gut 2011, ahead print. Persons with GERD symptoms ± Barrett‘s esophagus have increased insulin and insulin like growth factor-1 levels: evidence for a ... | read article |
| 2011-10-28 | Erholung vom Alltag durch Verklärung Source: iGERD NEWS ROOM Körper und Seele orchestrieren unser Befinden. Pausen der Verklärung helfen uns die Balance zu finden und zu erhalten. ... | read article |
| 2011-10-28 | Patienten/Innen Infos zur Fundoplikatio: Ablauf und worauf man nach der OP achten soll. Source: iGERD NEWS ROOM Hier informieren wir über den Ablauf bei Fundoplikatio und was Sie nach der OP beachten sollten.... | read article |
| 2011-10-27 | Buried glands after radiofrequency (HALO) Ablation Source: Am J Gastroenterology 2011, ahead print. RFA, HALO, eliminates Barrett‘s esophagus in >90%. After RFA buried glands may occur in 0.9% of the cases. Adequate biopsy sampl... | read article |
| 2011-10-25 | Surveillance misses 90% of cancers Source: NEJM 2011; 365: 1375-83. Less than 10% of esophageal reflux associated cancers are detected by current surveillance strategies. ... | read article |
| 2011-10-25 | Annual cancer incidence for Barrett's esophagus: 0.33% Source: Gut 2011, ahead print Cancer incidence for non-dysplastic Barrett's esophagus equals 0.33% per year. ... | read article |
| 2011-10-25 | Laparoscopic fundoplication: Nissen vs. Toupet Source: Surg Endosc 2011, ahead print. Laparoscopic Nissen (total) and partial (Toupet) Fundoplication are equally effective to eliminate GERD symptoms and reflux and ... | read article |
| 2011-10-25 | Ganzheitlicher Zugang & das Gesamtkunstwerk Mensch Source: iGERD NEWS ROOM Die spezialisierte Medizin neigt dazu, den ganzheitlichen Aspekt aus den Augen zu verlieren. Die Renaissance des holistischen, g... | read article |
| 2010-11-23 | Magnetic Sphincter Against Reflux: 2 year data. Source: Bonavina L. et al. Ann Surg 2010; 252: 857-862. The magnetic sphincter replaces fundoplication to restore the EGJ high pressure zone in GERD patients.... | read article |
| 2010-11-22 | Total vs. Partial Fundoplication: 5 year data. Source: Shaw JM, et al. Surg Endosc 2010; 24: 924-932. Total and partial fundoplication are equally effective to eliminate reflux and restore the anti reflux barrier at the esophagoga... | read article |
| 2010-10-01 | Bile Acids Cause Acidification And DNA Injury In Barrett‘s Epithelial Cells In Vitro. Source: Goldman A, Shahidullah M, Goldman D, et al. Gut 2010; ahead print. In Barrett‘s cells Bile Acids cause DNA injury by intracelluar acidification mediated via NO stimulated Na+/H+ - exchanger inhib... | read article |
| 2010-10-01 | The Squamo-Oxyntic Gap: A Novel Concept For Gastroesophageal Reflux Disease (GERD). Source: Chandrasoma P, Wijetunge S, DeMeester S, et al. Am J Surg Pathol 2010, ahead print. The squamo-oxyntic gap is a fascinating, novel histopathology concept to define GERD and assess the cancer risk, i.e. those with... | read article |
| 2010-09-27 | Five Years Data After Radiofrequency Ablation (RFA, HALO®, Barrx Medical, USA) of Non-Dysplastic Barrett‘s Esophagus Source: Fleischer DE, Overholt RF, Sharma VK, et al. Endoscopy 2010, ahead print. In 92% elimination of non-dysplastic Barrett‘s esophagus 5 years after radiofrequency ablation (RFA). ... | read article |
| 2010-09-16 | Increased Esophagogastric Junction Distensibility in GERD. Source: Gastrointestinal Endoscopy 2010; 72: 272-8. Increased distensibilty of the esophagogastric junction contributes to reflux.... | read article |
| 2010-09-13 | Effective Fundoplication Regresses Barrett’s Esophagus And Reduces Caner Risk. Source: J Gastroinest Surg 2010, ahead print. 0.36% vs. 2.6% annual cancer risk 9 years after effective vs. ineffective fundoplication.... | read article |
| 2010-08-12 | Arguments for Radiofrequency ablation (RFA, HALO®, Barrx Medical) of Non-Dysplastic Barrett‘s esophagus (NDBE). Source: iGERD literature review Biological and genetic characteristics justify ablation of nondysplastic Barrett's.... | read article |
| 2010-08-10 | Cancer Risk For Barrett‘s Esophagus: 0.4% per Year. Source: GUT 2010; 59: 1030-36. Study in > 40.000 Barrett's patients: 0.4% annual cancer risk.... | read article |
| 2010-08-05 | Barrett's: Radiofrequency Ablation + Fundoplication: Superior to Combination With PPI Treatment. Source: Surg Endosc 2010; accepted July 2010; ahead print. Radiofrequency ablation (RFA)+fundoplication is more effective to eliminate Barrett's: 94.7% vs. 75% with PPI after 12 months .... | read article |
| 2010-08-04 | Myofibroblasts in Barrett‘s Esophagus. Source: Indian J Pathol Microbiol 2010; Apr-Jun; 53(2): 262-6. Immunhistochemistry markers of Myofibroblasts colocalize with Barrett's epithelium and are absent in normal epithelium.... | read article |
| 2010-08-04 | Gastric Distension Impairs The Anti-Reflux Barrier: Cause for GERD. Source: Ann Surg 2010; 252: 57-62. Gastric distension dramatically impairs anti-reflux barrier function.... | read article |
| 2010-08-04 | Effective Fundoplication Reduces The Genetic Stress Within Barrett‘s Esophagus. Source: Ann Surg 2010; 252(1): 63-9. Effective fundoplication reduces the genetic stress of the esophagus.... | read article |
| 2010-08-04 | Increased Reflux In Barrett‘s Esophagus. Source: Neurogastroenterol Motil 2010, Jun 17, ahead print. Authors compare reflux in normals, erosive esophagitis and Barrett's esophagus, using impedance pH monitoring. Great study.... | read article |
| 2010-07-09 | Progression of Barrett's Esophagus With Low Grade Dysplasia: Impact of Pathology Report. Source: Am J Gastroenterol 2010, 105: 523-30. Barrett's esophagus (BE) results from gastroesophageal reflux and represent columnar lined esophagus with goblet cells.... | read article |
| 2010-07-09 | Biomarkers Predict Cancer Risk in Barrett's Esophagus: Aneuploidy, p53- and p16- Loss of Heterozygosity (LOH). Source: Am J Gastroenterol 2010; 105: 490-502. Barrett's esophagus (columnar lined esophagus with goblet cells) harbors the risk for malignant progression (0.5% - 5.3% per yea... | read article |
| 2010-07-09 | Inflammatory Bowel Disease and Barrett's: Common Genetics And Histopathology. Source: Arch Pathol Lab Med 2010; 134: 896-906. Goblet cells within columnar lined esophagus define intestinal metaplasia or Barrett's esophagus (BE). Be results from gastroeso... | read article |
| 2010-05-26 | LOTUS Trial 3 Years Data: Proton Pump Inhibitor (PPI) And Antireflux Surgery Reduce Changes Within Squamous Lined Esophagus Source: Am J Gastroenterology 2010; 105(5): 1015-23 The famous LOTUS trial compares medical therapy (proton pump inhibitor; PPI) versus laparoscopic antireflux surgery for the mana... | read article |
| 2010-05-25 | Columnar Lined Esophagus: Role Of The Stroma Underlying The Epithelium For Cancer Development Source: PNAS 2010; 107 (5): 2177-2182 Gastroesophageal reflux disease (GERD) causes columnar lined esophagus, which may progress towards intestinal metaplasia (IM, Ba... | read article |
| 2010-05-25 | Orchestration Of Columnar Lined Esophagus (CLE): Inflammatory Bowel Disease (IBD) Of The Esophagus Source: European Surgery 2010; 42/2: 69-71 Gastroesophageal reflux disease (GERD) induces columnar lined esophagus (CLE), which may progress towards cancer via a sequence ... | read article |
| 2010-05-25 | Metaanalysis: Symptoms And Barrett's Esophagus Source: American Journal of Gastroenterology 2010; May, ahead print Barrett's esophagus (BE) results from gastroesophageal reflux disease (GERD) and is associated with an increased risk for the de... | read article |
| 2010-05-25 | Acid Exposure Increased During Recumbent Asleep vs. Recumbent Awake Source: American Journal of Gastroenterology 2010; May, ahead print pH monitoring represents the gold standard for the diagnosis of gastroesophageal reflux disease (GERD). Acid exposure (pH<4.0) w... | read article |
| 2010-05-25 | High Dose Proton Pump Inhibitor (PPI) Therapy Is Superior In Obese Patients With Gastroesophageal Reflux Disease (GERD) Source: American Journal of Gastroenterology 2010; May, ahead print Gastroesophageal reflux disease (GERD) is associated with obesity. Thus GERD management becomes an important aspect in the manag... | read article |
| 2010-05-25 | Impedance pH Monitoring: Erosive Esophagitis, Nonerosive Reflux Disease (NERD) And Controls Source: American Journal of Gastroenterology 2010; May, ahead print Gastroesophageal reflux disease (GERD is a spectrum disease ranging from severe symptoms and esophagitis towards mild symptoms a... | read article |
| 2010-05-25 | Do Not Hesitate To Offer Nissen To Patients With Gastroesophageal Reflux Disease (GERD): 5 Year Outcomes From The Netherlands Source: Laparoscopic Nissen fundoplication, the major tool for the surgical management of gastroesophageal reflux disease (GERD), aims ... | read article |
| 2010-05-25 | Dual High Pressure Zone Indicates Failed Fundoplication Source: J Am Coll Surg 2010; 210: 611-619 Antireflux surgery is the surgical modality of choice for the treatment of gastroesophageal reflux disease (GERD) and is most fr... | read article |
| 2010-05-25 | New Proton Pump Inhibitor: E3710 Source: Proton pump inhibitor (PPI) is the mainstay for the medical treatment of gastroesophageal reflux disease (GERD). PPI acts by sel... | read article |
| 2010-05-25 | Esomeprazole Against Reflux-Induced Sleep Disturbances Source: Aliment Pharmacol & Therapeutics 2010; ahead print Persons with gastroesophageal reflux disease (GERD) frequently perceive reflux induced sleep disturbances during the night. Thes... | read article |
| 2010-05-25 | Reconfirmed: Esomeprazole Is The Most Potent Proton Pump Inhibitor Source: Aliment Pharmacol & Therapeutics 2010; ahead print Proton pump inhibitor (PPI) serves for the standard medical treatment of choice for the management of gastroesophageal reflux di... | read article |
| 2010-05-25 | Gastroesophageal Reflux And Serum Lipid Levels: A Positive Correlation Source: Neurogastroenterol Motil, 2010, May, ahead print The association of gastroesophageal reflux disease (GERD) and the metabolic syndrome is not well established. Recent evidence in... | read article |
| 2010-05-25 | Symptom Perception Differs Along The Spectrum Of Gastroesophageal Reflux Disease (GERD) Source: Dig Dis Sci 2010, May, ahead print Gastroesophageal reflux disease is defined by the typical and atypical symptom. Based on the presence or absence of endoscopical... | read article |
| 2010-05-25 | Economics: Gastroesophageal Reflux Disease (GERD) Affects Productivity And Causes Sick Leave. Source: Eur J Med Res 2010; 15(3): 124-30 Due to the symptoms (heartburn, regurgitation, coughing) gastroesophageal reflux disease (GERD) impairs well being. Evidence ind... | read article |
| 2010-04-22 | Justified: Radiofrequency Ablation (HALO®) And Anti-Reflux Surgery for Non-Dysplastic Barrett‘s Esophagus (BE). Source: Dig Dis Sci 2010 (April), ahead print Barrett‘s esophagus (=goblet cell containing columnar lined esophagus) results from gastroesophageal reflux and is associated wi... | read article |
| 2010-04-15 | Anti-reflux surgery and cancer prevention: does surgical anatomy matter? Source: Martin Riegler With interest iGERD followed the article by Lagergren et al. (1), entitled „The risk of esophageal adenocarcinoma after antirefl... | read article |
| 2010-04-11 | Predictors For Recurrence Of Dysplasia And Cancer After Photodynamic Therapy (PDT) Of Barrett‘s Esophagus Source: Gastrointest Endosc. 2010; 71: 697-703 SUMMARY: PDT aims to eliminate dysplasia and early cancer in Barrett‘s esophagus (BE). Three years after PDT, 17% ... | read article |
| 2010-04-11 | Nondysplastic Barrett‘s Esophagus: Arguments For Radiofrequency Ablation (RFA) and Fundoplication Source: SUMMARY: Persons with nondysplastic Barrett‘s esophagus (BE) harbor a 0.5%-5.3% annual risk for cancer development. ... | read article |
| 2010-04-09 | Increased Cancer Risk After Fundoplication Due To Study Design? Source: Gastroenterology 2010; 138: 1297-1301 Gastroesophageal reflux disease (GERD) is associated with an increased risk for the development of esophageal cancer. Reflux ind... | read article |
| 2010-04-08 | GERD: Eosinophils And Dysphagia Source: Dis Dis Sci 2010, 55: 967-972 GERD may be associated with dysphagia, which can not be explained by manometry, pH monitoring, endoscopy, and symptoms. ... | read article |
| 2010-04-01 | Barrett‘s Esophagus: Fibroblasts Mediate CDX-2 Expression In Squamous Epithelium Via NF Kappa B Source: Lab Invest 2010, ahead print SUMMARY: CDX 2 mediates Barrett‘s esophagus. Upon acid exposure fibroblasts release heparin binding EGF like growt... | read article |
| 2010-03-30 | Barrett‘s Esophagus Expresses CDX2 in Squamous Epithelium: Paving The Road Towards Intestinal Metaplasia Source: Gastroenterology 2010, march, ahead print SUMMARY: In vivo: In Barrett‘s esophagus squamous epithelium more frequently expresses CDX2, when compared to non-Barrett... | read article |
| 2010-03-30 | GERD Symptoms Do Not Represent An Adequate Predictive Marker For Esophageal Adenocarcinoma Risk Source: Nature Reviews 2010; 10: 87-101 SUMMARY: The majority of cases of esophageal adenocarcinoma develop in persons without a history of GERD symptoms. ... | read article |
| 2010-03-23 | GERD and Barrett‘s Esophagus: IBD of the Esophagus? Source: Am J Physiol, Gastrointerstinal Liver Physiol 2010, ahead print. The current understanding of the GERD pathogenesis is based on a simplified, mechanistic model: acid/gastric contents causes inj... | read article |
| 2010-02-24 | Newsletter Day 5: The last day!Endoscopy can not assess the EG junction! IM but not CM harbors significant genome abnormalities! Source: Martin Riegler The last day of the meeting was opened by a state of the art lecture of Dr. Stuart Spechler, Dallas, on the evolving concepts re... | read article |
| 2010-02-23 | Newsletter Day 4: Are Goblet Cells No More Required For The Definition of Barrett's Esophagus? Source: Are Goblet Cells No More Required For The Definition of Barrett's Esophagus? Columnar Lined Esophagus Represents ... | read article |
| 2010-02-21 | Newsletter Day 3: Medical and Surgical Aspects of Esophageal and Foregut Disorders: Pathophysiology and Treatment Source: Martin Riegler Endoscopy is not reliable to assess the esophagogastric junction (EGJ). It requires the histopathology of biopsies from the EJG.... | read article |
| 2010-02-20 | Newsletter Day 1: Medical and Surgical Aspects of Esophageal and Foregut Disorders: Pathophysiology and Treatment Source: Martin Riegler 30-40% of GERD patients do not respond to PPI and should get alternative therapy (surgery).... | read article |
| 2010-02-20 | Newsletter Day 2: Medical and Surgical Aspects of Esophageal and Foregut Disorders: Pathophysiology and Treatment Source: Martin Riegler 30-40% of GERD patients do not respond to PPI and should get alternative therapy (surgery).... | read article |
| 2010-02-02 | Factors Predicting Cancer Risk in Persons With Barrett's Esophagus Source: Am J Gastroenterol 2010, ahead print Barrett's esophagus (BE) results from gastroesophageal reflux and is defined by the presence of columnar lined esophagus with in... | read article |
| 2010-02-02 | Gradients Across The Columnar Lined Esophagus: Novel Understanding Of Barrett's Esophagus Source: J Gastrointest Surg 2010, ahead print Barrett's esophagus (BE) is columnar lined esophagus with intestinal metaplasia (=goblet cells), results from gastroesophageal r... | read article |
| 2010-02-02 | Active Treatment Of Barrett's Is Justified: Novel Definitions & Concepts Source: Gastroenterology 2010 Barrett's esophagus, this is columnar lined esophagus with intestinal metaplasia (=goblet cells within the columnar epithelium),... | read article |
| 2010-01-25 | Barrett's Esophagus And Colorectal Cancer Source: Am J Gastroenterol 2010, ahead print Barrett's esophagus (BE) results from gastroesophageal reflux, is defined by the presence of columnar lined esophagus containing... | read article |
| 2010-01-25 | Cholecystectomy And GERD Symptoms Source: Ann Surg 2010; 251: 40-45 Recent evidence indicated that the symptoms of gastroesophageal reflux disease (GERD) worsen after cholecystectomy.... | read article |
| 2010-01-25 | Radiofrequency Ablation And Fundoplication For Barrett's Esophagus Source: J Thorac Cardiovasc Surg 2010: ahead print Barrett's esophagus results from gastroesophageal reflux disease (GERD), is columnar lined esophagus containing goblet cells ("i... | read article |
| 2010-01-25 | Nissen Versus Toupet Fundoplication: Metaanalysis Source: J Gastrointest Surg 2010; ahead print (DeMeester Festschrift) Conceptually anti reflux surgery creates a fundic wrap around the distal esophagus adjacent to the esophagogastric junction.... | read article |
| 2010-01-25 | Esophagectomy: Anti-Reflux Anastomosis Source: Reflux of gastric content into the remnant esophagus represents a frequent problem after esophagectomy and gastric pull up. In a... | read article |
| 2009-11-30 | Barrett's Esophagus & Irregular Squamocolumnar Junction Source: Eur J Gastroenterol Hepatol 2009; 10 (ahead print). Barrett's esophagus is caused by gastroesophageal reflux, represents intestinal metaplasia within columnar lined esophagus and h... | read article |
| 2009-11-30 | The 21 Years "Natural History" of GERD Source: Scand J Gastroenterol 2009; 44: 1277-87 This study by Falkenbach et al. investigated the long term follow up of persons with gastroesophageal reflux disease. The study ... | read article |
| 2009-11-30 | The LOTUS Trial: Fundoplication vs. PPI on Squamous Lined Esophagus Source: Am J Gastroenterol 2009; Nov 10 (ahead print) The LOTUS trial is a long term open parallel group multicenter randomized controlled trial to compare laparoscopic fundoplicatio... | read article |
| 2009-11-10 | Limitations of the Prague Classification: Consequences for Radiofrequency Ablation of Barrett's Esophagus (HALO®, Barrx Medical, USA) Source: The Prague classification aims to catalog endoscopically visible columnar lined esophagus. This is columnar lining interposed be... | read article |
| 2009-11-09 | Markers for Neoplastic Progression in Barrett's Esophagus Source: Am J Gastroenterol 2009; 104: 2673-2680 Barrett's esophagus, this is columnar lined esophagus with intestinal metaplasia (=goblet cells within cardiac mucosa in H&E sta... | read article |
| 2009-11-09 | Fundoplication Promotes Regression of Barrett's Esophagus Source: Arch Surg 2009; 144(19): 921-927 Barrett's esophagus results from gastroesophageal reflux, is columnar lined esophagus with intestinal metaplasia within H&E stai... | read article |
| 2009-11-09 | Ten - Year Data of Laparoscopic vs. Conventional Fundoplication: > 90% Symptom Resolution Source: Ann Surg 2009; ahead print This randomized clinical trial coming from a group of well known specialists in the field compared the impact of conventional an... | read article |
| 2009-11-09 | Gender & Outcome of Fundoplication Source: World J Surg 2009, ahead print This study coming from a well known group of Austrialian surgeons investigated gender differences regarding the preoperative fin... | read article |
| 2009-11-09 | Colors vs. Lines: High Resolution vs. Conventional Manometry of the Esophagogastric Junction Pressure Zone Source: J Gastrointest Surg 2009, ahead print Esophageal manometry aims to assess the characteristics of the esophagogastric junction pressure zone, the so called lower esoph... | read article |
| 2009-11-09 | Let Us Move Closer to the EG-Junction Pressure Zone: Multi Level pH Monitoring Source: Am J Gastroenterol 2009, ahead print During classical pH monitoring the pH probe is placed 5 cm above the upper limit of the esophagogastric junction pressure zone (... | read article |
| 2009-11-09 | Cardia-Induced Enlargement Of The Esophageal Hiatus Reflects The Break Down Of The Anti-Reflux Barrier in GERD Source: J Gastroinest Surg 2009; ahead print Gastroesphageal reflux disease (GERD) results from the distortion and break down of the anti reflux barrier at the esophagogastr... | read article |
| 2009-11-09 | OUT NOW: Endoscopic Surgery And Radiofrequency Ablation For Dysplastic Barrett's Esophagus And Early Cancer Source: Clin Gastroenterol & Hepatol 2009; ahead print Background: Columnar lined esophagus results from gastroesophageal reflux. Via a sequence involving cardiac mucosa, intes... | read article |
| 2009-11-09 | iGERD Comment on Endoscopic Surgery And Radiofrequency Ablation For Dysplastic Barrett's Esophagus And Early Cancer Source: Clin Gastroenterol & Hepatol 2009; ahead print iGERD comment: The authors are to be congratulated for their outstanding performance, expertise in advanced endoscopy an... | read article |
| 2009-10-15 | Reflux Esophagitis Starts in the Submucosa Source: Gastroenterology 2009; in press Gastroesophageal reflux is believed to cause damage and inflammation of the squamous epithelium. Acid and other components of th... | read article |
| 2009-09-15 | NEWS from Hawaii: Surfing And Gastroesophageal Reflux Disease (GERD) Source: Clin J Sport Med 2009; 19/5: 388-393. Gastroesophageal reflux disease results from the failure of the pressure zone at the esophagogastric junction. Conceptually, ade... | read article |
| 2009-09-03 | HALO® Radiofrequency Ablation of Dysplastic Barrett‘s Esophagus: Nodules & Inter - Observer Variability Source: N Engl J Med 2009; 361: 10: 1021-22. Barrett‘s esophagus results from gastroesophageal reflux, is columnar lined esophagus with intestinal metaplasia (goblet cells w... | read article |
| 2009-09-02 | Reconfirmed: Efficacy of Radiofrequency Ablation for Barrett‘s Esophagus Source: Surg Endosc 2009; ahead print. Radiofrequency ablation (RFA) represents a novel technology for the endoscopic elimination of Barrett‘s esophagus (BE). BE is co... | read article |
| 2009-08-12 | Increasing Incidences of Esophageal & Cardia Adenocarcinoma in England Source: Aliment Pharm Ther 2009; ahead print Four major types of cancers can develop within the esophagus and the stomach: esophageal squamous cell cancer, adenocarcinoma of... | read article |
| 2009-08-12 | Impedance pH-Monitoring in GERD, Functional Heartburn And Controls Source: Journal of Gastroenterology & Hepatology 2009; 24: 1113-18 Impedance pH monitoring serves to assess reflux events, irrespective of the pH of the reflux. Thus the technology measures acid ... | read article |
| 2009-08-12 | Scintigraphic Visualization Of The Postprandial Acid Pocket Source: Gut 2009; ahead print Here we report an outstanding study that profoundly adds to the understanding of the pathophysiology underlying post prandial ac... | read article |
| 2009-08-07 | Gender Medicine: Asymptomatic Women Have Barrett's Source: Gastrointest Endoscopy 2009; July; ahead print Gastroesophageal reflux disease (GERD) means that gastric content refluxes back into the esophagus causing symptoms and inflamma... | read article |
| 2009-08-07 | Fascinating: The Dilated End Stage Esophagus Pockets The Acid Source: Am J Gastroenterol 2009; ahead print Esophageal pH monitoring represents the standards diagnostic tool for the assessment of gastroesophageal reflux disease (GERD). ... | read article |
| 2009-07-30 | Esophagus: Aspirin Does Not Prevent Dysplasia And Adenocarcinoma Source: Eur J Cancer Prev 2009; Jul 17 (ahead print) Via a sequence including low and high grade dysplasia Barrett's esophagus may progress towards adenocarcinoma of the esophagus (... | read article |
| 2009-07-30 | Egypt Keeps Up With The West: Frequency of Barrett's Esophagus Source: World J Gastroenterol 2009; 15(28): 3511-3515 Attention towards Barrett's esophagus is justified due to the increased cancer risk associated with this condition (0.5% per yea... | read article |
| 2009-07-30 | Adiponectin And Barrett's Esophagus Source: Gut 2009; ahead print Gastroesophageal reflux disease (GERD) harbors the risk for esophageal adenocarcinoma. This highly lethal tumor develops along a... | read article |
| 2009-07-30 | Reflux Profile And Esophageal Morphology Source: Neurogastroenterol Motil 2009; 21: 807-12 Gastroesophageal reflux disease (GERD) causes symptoms (heartburn, regurgitation etc.) and morphologic damage of the esophagus (... | read article |
| 2009-07-30 | Prediction of Dysphagia After Nissen Fundoplication: Impact of Intraluminal Impedance And Manometry? Source: Dis Esoph 2009; ahead print Laparoscopic fundoplication represents the gold standard for the surgical management of gastroesophageal reflux disease (GERD).... | read article |
| 2009-07-30 | Who Does Not Feel It, Has It: Obesity Indicates Asymptomatic Gastroesophageal Reflux Disease (GERD) Source: Obes Surg 2009; 19: 1143-1149 Gastroesophageal reflux disease (GERD) is associated with abnormal esophageal manometry and acid exposure.... | read article |
| 2009-07-30 | Esophageal Acid Exposure And Impairment Of Lower Esophageal Sphincter Function is Associated With Increased Body Mass Index Source: J Gastrointest Surg 2009; 13: 1440-47 Increasing evidence indicates a positive association between gastroesophageal reflux disease (GERD) and obesity. The functional ... | read article |
| 2009-07-30 | Novel Approach Towards Transient Lower Esophageal Sphincter Relaxations Source: Am J Physiol 2009; 297: G71-G75 Gastroesophageal reflux disease (GERD) results from impairment of the antireflux barrier within the distal esophagus. During man... | read article |
| 2009-07-30 | Elimination of Dysplasia and Cancer With Endoscopic Surgery And Radiofrequency Ablation (HALO®) Source: Clin Gastroenterol Hepatol 2009, Jul; ahead print Gastroesophageal reflux causes columnar lined esophagus (CLE), which may progress towards cancer via a sequence involving cardia... | read article |
| 2009-07-28 | Radiofrequency Ablation Is Highly Effective to Eliminate Dysplasia in Barrett‘s Esophagus Source: Barrett‘s esophagus (BE) is columnar lined esophagus (CLE) with intestinal metaplasia. BE results from gastroesophageal disease ... | read article |
| 2009-07-23 | Towards Adenocarcinoma of the Esophagus: p53 & Ki-67 Source: P53 and KI-67 overexpression in gastroesophageal reflux disease - Barrett's esophagus and aadenocarcinoma sequence.... | read article |
| 2009-07-23 | Correlation of Histopathology and pH Monitoring in GERD Source: Exposure of the esophagus with gastric content is the pathophysiologic basis of gastroesophageal reflux disease. Overtime reflux... | read article |
| 2009-07-23 | Fundoplication After Radiofrequency Ablation of Barrett's Esophagus? Source: Shaheen et al. (1) demonstrated that radiofrequency ablation (RFA) of Barrett's esophagus is highly effective for elimination of... | read article |
| 2009-07-23 | Minimal Invasive Esophagectomy: The Vienna Experience Source: When it can not be avoided it happens. The same is true for esophageal cancer. The surgical treatment of esophageal cancer (squa... | read article |
| 2009-06-04 | The Spectrum of Non-Erosive Reflux Disease (NERD) Source: Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease... ... | read article |
| 2009-06-04 | Endoscopy Dominates Histopathology: This Explains The Confusion Around The „Cardia“ Source: With interest iGERD read the article by Glickman et al. (1), entitled „Multilayered epithelium in mucosal biopsy specimens from ... | read article |
| 2009-06-02 | Effective Against Barrett‘s Esophagus: Radiofrequency Ablation (HALO®; Barrx Medical) Works in Community Practice Source: Barrett‘s esophagus is premalignant columnar lined esophagus, results from gastroesophageal reflux and harbors a 0.5% annual ris... | read article |